galanin (Pig)


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O
InChIKey WVFODTWUOPGPAP-CIJSCKBQSA-N
Sequence GWTLNSAGYLLGPHAIDNHRSFHDKYGLA

Chemical properties

Hydrogen bond acceptors 44
Hydrogen bond donors 45
Rotatable bonds 99
Molecular weight (Da) 3209.6

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pKi 9.64 10.12 10.6 Guide to Pharmacology
GAL1 GALR1 Human Galanin A pKd 9.1 9.1 9.1 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pKi 9.02 9.02 9.02 Guide to Pharmacology
GAL3 GALR3 Human Galanin A pKi 8.01 8.01 8.01 Guide to Pharmacology
GAL3 GALR3 Rat Galanin A pKi 8.14 8.14 8.14 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pKi 8.98 9.14 9.3 Guide to Pharmacology
GAL1 GALR1 Rat Galanin A pKi 9.09 9.54 10.0 Guide to Pharmacology
GAL1 GALR1 Rat Galanin A pKd 9.13 9.13 9.13 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pIC50 9.8 9.82 9.85 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pEC50 8.09 8.09 8.09 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pIC50 9.46 9.46 9.46 Guide to Pharmacology
GAL3 GALR3 Human Galanin A pIC50 7.92 7.92 7.92 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pEC50 7.74 7.74 7.74 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pIC50 9.34 9.38 9.43 Guide to Pharmacology
GAL1 GALR1 Rat Galanin A pIC50 10.15 10.19 10.22 Guide to Pharmacology