galanin(10-29) (pig)


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O
InChIKey UAOTUUKSRUXJQS-UDKLMHSUSA-N
Sequence LLGPHAIDNHRSFHDKYGLA

Chemical properties

Hydrogen bond acceptors 31
Hydrogen bond donors 31
Rotatable bonds 71
Molecular weight (Da) 2260.2

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL3 GALR3 Rat Galanin A pKi 6.0 6.0 6.0 Guide to Pharmacology
GAL1 GALR1 Rat Galanin A pKi 6.0 6.0 6.0 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL2 GALR2 Rat Galanin A pIC50 6.0 6.0 6.0 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pEC50 6.0 6.0 6.0 Guide to Pharmacology