galanin(1-15)


SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)O
InChIKey LOXLDVDBPRBBLT-GDRYISODSA-N
Sequence GWTLNSAGYLLGPHA

Chemical properties

Hydrogen bond acceptors 21
Hydrogen bond donors 21
Rotatable bonds 44
Molecular weight (Da) 1555.8

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Rat Galanin A pKi 7.94 8.23 8.52 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pKi 8.46 8.46 8.46 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pKi 9.15 9.15 9.15 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pIC50 8.77 8.77 8.77 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pEC50 9.14 9.14 9.14 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pIC50 8.61 8.61 8.61 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pEC50 7.19 7.19 7.19 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pIC50 8.13 8.13 8.13 Guide to Pharmacology