SCH 37370


SMILES Clc1ccc2c(c1)CCc1c(C2=C2CCN(CC2)C(=O)C)nccc1
InChIKey FLTBEMVEAFMWDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 352.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 6.5 6.5 6.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pIC50 6.2 6.2 6.2 Guide to Pharmacology
PAF PTAFR Human Platelet-activating factor A pIC50 6.08 6.14 6.21 ChEMBL
H1 HRH1 Human Histamine A pIC50 7.0 7.0 7.0 ChEMBL