α-helical CRF


SMILES None
InChIKey TYEPJUPPTULOKD-GVKLFNHCSA-N
Sequence DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF1 CRFR1 Human Corticotropin-releasing factor B1 pKd 7.3 7.55 7.8 Guide to Pharmacology
CRF2 CRFR2 Mouse Corticotropin-releasing factor B1 pKd 9.0 9.05 9.1 Guide to Pharmacology
CRF2 CRFR2 Rat Corticotropin-releasing factor B1 pKd 8.3 8.35 8.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database