gastrin releasing peptide(14-27) (human) (Human)


SMILES CSCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)O)C(C)C
InChIKey MJHJYGACUDLDMG-QEJDUTAOSA-N
Sequence MYPRGNHWAVGHLM

Chemical properties

Hydrogen bond acceptors 22
Hydrogen bond donors 21
Rotatable bonds 49
Molecular weight (Da) 1667.8

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BB1 NMBR Human Bombesin A pIC50 6.83 6.87 6.91 Guide to Pharmacology
BB2 GRPR Human Bombesin A pIC50 9.72 9.75 9.77 Guide to Pharmacology
BB1 NMBR Rat Bombesin A pIC50 6.64 6.64 6.64 Guide to Pharmacology