VUF5574


SMILES COc1ccccc1NC(=O)Nc1nc(nc2c1cccc2)c1cccnc1
InChIKey YRAFEJSZTVWUMD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 371.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A3 AA3R Human Adenosine A pKi 8.39 8.39 8.39 Guide to Pharmacology
A1 AA1R Rat Adenosine A pKi 5.0 5.0 5.0 Guide to Pharmacology
A2A AA2AR Rat Adenosine A pKi 5.0 5.0 5.0 Guide to Pharmacology
A2B AA2BR Human Adenosine A pKi 5.0 5.0 5.0 ChEMBL
A3 AA3R Human Adenosine A pKi 5.39 6.89 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database