CHEMBL100729


SMILES CCN1CC[C@]2(c3cccc(O)c3)Cc3[nH]c(C(=O)N(CC)CC)c(C)c3C[C@H]2C1
InChIKey LCXJNOQXEGZLDX-UQBPGWFLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 409.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pKi 5.22 5.77 5.89 ChEMBL
μ OPRM Mouse Opioid A pKi 6.39 6.64 6.89 ChEMBL
δ OPRD Mouse Opioid A pKi 5.45 7.74 9.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 6.33 6.96 7.58 ChEMBL