kynurenic acid


SMILES OC(=O)c1cc(=O)c2c([nH]1)cccc2
InChIKey HCZHHEIFKROPDY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 189.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Human Orphan A pEC50 3.9 4.16 4.41 Guide to Pharmacology
GPR35 GPR35 Mouse Orphan A pEC50 4.96 4.96 4.96 Guide to Pharmacology
GPR35 Q33BM1 Rat Orphan A pEC50 4.18 4.18 4.18 ChEMBL
GPR35 GPR35 Human Orphan A pEC50 4.41 4.41 4.41 ChEMBL
GPR35 GPR35 Human Orphan A pIC50 4.41 4.41 4.41 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 7.75 7.75 7.75 ChEMBL
GPR35 Q33BM1 Rat Orphan A pEC50 5.15 5.15 5.15 Guide to Pharmacology