CHEMBL102347


SMILES COc1cc(CCN)c2c(c1OC)OCC2
InChIKey GGGQVCBWGWDHMQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 223.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.21 5.21 5.21 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.28 6.39 6.51 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.96 6.45 6.93 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.19 5.81 6.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pEC50 5.7 5.7 5.7 ChEMBL