CHEMBL154787


SMILES COc1ccccc1C1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
InChIKey YMNMPQRISIFNCA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 458.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 6.1 6.1 6.1 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 5.85 5.85 5.85 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 7.0 7.0 7.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 9.1 9.1 9.1 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.82 5.82 5.82 ChEMBL