CHEMBL104453


SMILES c1ccc(CN2CCC(n3cccc3-c3cnco3)CC2)cc1
InChIKey JTHXHSNJAJMWTQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 307.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.0 5.0 5.0 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.2 7.2 7.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.11 6.11 6.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.21 6.36 6.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database