MM07


SMILES NCCCC[C@@H](C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)Cc1ccccc1)CCSC)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N2[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CC(C)C)CCCNC(=N)N)CCC2
InChIKey RKFGCZWTURNFPN-SVENNQHVSA-N
Sequence CRPRLCHKGPMPF

Chemical properties

Hydrogen bond acceptors 21
Hydrogen bond donors 19
Rotatable bonds 34
Molecular weight (Da) 1538.7

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 8XZH

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
apelin APJ Human Apelin A pEC50 9.5 9.5 9.5 Guide to Pharmacology
apelin APJ Human Apelin A pEC50 5.67 7.12 9.54 ChEMBL