CHEMBL160266


SMILES Clc1ccc(N2CCN(Cc3cnn4c(N5CCN(Cc6ccccc6)CC5)cccc34)CC2)cc1
InChIKey GYWHDZIJHYATFG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 500.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.75 6.75 6.75 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.39 6.39 6.39 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.19 6.29 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database