CHEMBL160454


SMILES C[Si](C)(C)c1cccc2c(CN3CCN(c4ccc(Cl)cc4)CC3)cnn12
InChIKey VLCYCTQMMKCUDI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 398.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.15 5.15 5.15 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.55 8.55 8.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.7 5.7 5.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.51 5.53 5.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database