AZ8838


SMILES CCCc1cc(F)ccc1[C@@H](c1ncc[nH]1)O
InChIKey IDFPQEHZYBXIFO-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 234.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 5NDD

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAR2 PAR2 Human Proteinase-activated A pKd 6.46 6.46 6.46 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAR2 PAR2 Human Proteinase-activated A pIC50 5.73 5.73 5.73 Guide to Pharmacology
PAR2 PAR2 Human Proteinase-activated A pIC50 5.38 5.38 5.38 ChEMBL