CHEMBL1632410


SMILES c1ccc(COC[C@H]2CC[C@@H](c3c[nH]cn3)O2)cc1
InChIKey RETVAMKTDRMQFH-HIFRSBDPSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 258.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 4.87 4.88 4.9 ChEMBL
H3 HRH3 Human Histamine A pKi 5.16 5.18 5.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 4.9 4.92 4.94 ChEMBL
H3 HRH3 Human Histamine A pEC50 5.0 5.0 5.01 ChEMBL