CHEMBL1681848


SMILES O=C(NCc1ccc(F)c(F)c1)c1cnc(N2CCN(C3CCN(Cc4ccc(Cl)cc4)CC3)CC2)c(Cl)c1
InChIKey FMYKWJDOTAPBPQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 573.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR3 CXCR3 Human Chemokine A pKi 7.4 7.4 7.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR3 CXCR3 Rat Chemokine A pIC50 7.01 7.01 7.01 ChEMBL
CXCR3 CXCR3 Mouse Chemokine A pIC50 7.08 7.08 7.08 ChEMBL
CXCR3 CXCR3 Human Chemokine A pIC50 7.4 7.4 7.4 ChEMBL