octopamine


SMILES NCC(c1ccc(cc1)O)O
InChIKey QHGUCRYDKWKLMG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 153.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Ligand site mutations α2A

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Rat Trace amine A pEC50 5.9 5.9 5.9 Guide to Pharmacology
TA1 TAAR1 Mouse Trace amine A pEC50 5.4 5.6 5.8 Guide to Pharmacology
TA1 TAAR1 Human Trace amine A pEC50 8.24 8.24 8.24 Drug Central
TA1 TAAR1 Rat Trace amine A pEC50 8.23 8.23 8.23 Drug Central
TA1 TAAR1 Mouse Trace amine A pEC50 8.24 8.24 8.24 Drug Central
TA1 TAAR1 Human Trace amine A pEC50 4.8 5.3 5.8 Guide to Pharmacology
TA1 TAAR1 Rat Trace amine A pEC50 5.89 5.89 5.89 ChEMBL