CHEMBL1739102


SMILES O=S(=O)(c1cccc(Cl)c1)c1n[nH]c2ccc(NC3CCNCC3)cc12
InChIKey AEFDXRNFDYCLFW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 390.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.78 5.78 5.78 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.81 6.81 6.81 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.92 7.92 7.92 ChEMBL