CHEMBL1080485


SMILES CNC(=O)Cn1c(=O)n(C2CCN([C@H]3CC[C@@H](C(C)C)CC3)CC2)c2ccccc21
InChIKey LRZFEWAQPXYWOH-KDURUIRLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 412.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 ChEMBL
κ OPRK Guinea pig Opioid A pKi 5.57 5.57 5.57 ChEMBL
δ OPRD Human Opioid A pKi 5.16 5.16 5.16 ChEMBL
μ OPRM Human Opioid A pKi 7.16 7.16 7.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 8.59 8.59 8.59 ChEMBL