PAF


SMILES CCCCCCCCCCCCCCCCOC[C@@H](OC(=O)C)COP(=O)(OCC[N+](C)(C)C)[O-]
InChIKey HVAUUPRFYPCOCA-AREMUKBSSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 25
Molecular weight (Da) 523.4

Drug properties

Molecular type Lipid
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 8XYD

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKi 7.5 7.7 7.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pIC50 8.2 8.2 8.2 Guide to Pharmacology