CHEMBL1782140


SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O
InChIKey ORYLQLGPWPORPN-VXNXHJTFSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 8
Rotatable bonds 12
Molecular weight (Da) 580.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 6.93 6.93 6.93 ChEMBL
μ OPRM Rat Opioid A pKi 9.82 9.82 9.82 ChEMBL
δ OPRD Human Opioid A pKi 9.22 9.22 9.22 ChEMBL
μ OPRM Human Opioid A pKi 9.82 9.82 9.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 9.38 9.38 9.38 ChEMBL