BIIE0246


SMILES NC(=NCCC[C@@H](C(=O)NCCn1c(=O)n(n(c1=O)c1ccccc1)c1ccccc1)NC(=O)CC1(CCCC1)CC(=O)N1CCN(CC1)C1c2ccccc2NC(=O)c2c1cccc2)N
InChIKey RSJAXPUYVJKAAA-JPGJPTAESA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 5
Rotatable bonds 16
Molecular weight (Da) 895.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y2 Q9ERC0 Rat Neuropeptide Y A pKi 8.0 8.0 8.0 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y2 NPY2R Human Neuropeptide Y A pIC50 8.5 8.5 8.5 Guide to Pharmacology