CHEMBL1795711


SMILES O=C(N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5)c1cccc(I)c1
InChIKey FGAFDGWRFOJPRY-XGTKUTNFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 572.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pKi 10.52 10.52 10.52 ChEMBL
μ OPRM Mouse Opioid A pKi 9.96 9.96 9.96 ChEMBL
δ OPRD Mouse Opioid A pKi 9.62 9.62 9.62 ChEMBL
δ OPRD Human Opioid A pKd 9.62 9.62 9.62 ChEMBL
δ OPRD Human Opioid A pKi 9.24 9.24 9.24 ChEMBL
κ OPRK Human Opioid A pKd 10.57 10.57 10.57 ChEMBL
κ OPRK Human Opioid A pKi 9.64 9.64 9.64 ChEMBL
μ OPRM Human Opioid A pKd 9.96 9.96 9.96 ChEMBL
μ OPRM Human Opioid A pKi 8.6 8.6 8.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database