CHEMBL1795712


SMILES C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@H](NC(=O)c2cccc(I)c2)CC[C@@]3(O)[C@H]1C5
InChIKey OWOWCHRXILVEKL-HJUABUFYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 558.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pKi 10.1 10.1 10.1 ChEMBL
μ OPRM Mouse Opioid A pKi 9.66 9.66 9.66 ChEMBL
δ OPRD Mouse Opioid A pKi 8.59 8.59 8.59 ChEMBL
δ OPRD Human Opioid A pKd 8.6 8.6 8.6 ChEMBL
δ OPRD Human Opioid A pKi 8.59 8.59 8.59 ChEMBL
κ OPRK Human Opioid A pKi 10.1 10.1 10.1 ChEMBL
κ OPRK Human Opioid A pKd 10.3 10.3 10.3 ChEMBL
μ OPRM Human Opioid A pKd 9.66 9.66 9.66 ChEMBL
μ OPRM Human Opioid A pKi 9.15 9.15 9.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database