CHEMBL179648


SMILES c1ccc(CN2CCN(CC3CCc4ccccc4O3)CC2)cc1
InChIKey AJZBPCAHQHCXMX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.75 6.95 7.14 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.68 7.7 7.71 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.44 8.44 8.44 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.78 6.8 6.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.68 7.68 7.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database