CHEMBL1803026


SMILES COc1cc(CN2CCN(c3ccccc3OC)CC2)ccc1OCCCCc1cn(CCCCCCCCCCn2cc(CCCCOc3ccc(CN4CCN(c5ccccc5OC)CC4)cc3OC)nn2)nn1
InChIKey KGEGCSUUIDNIBO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 16
Hydrogen bond donors 0
Rotatable bonds 33
Molecular weight (Da) 1040.7

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.52 6.52 6.52 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.13 7.13 7.13 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.77 7.93 8.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database