CHEMBL1803027


SMILES COc1cc(CN2CCN(c3ccccc3OC)CC2)ccc1OCc1cn(CCOCCOCCn2cc(COc3ccc(CN4CCN(c5ccccc5OC)CC4)cc3OC)nn2)nn1
InChIKey LQTCRFLMOJHQHE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 18
Hydrogen bond donors 0
Rotatable bonds 25
Molecular weight (Da) 932.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.41 6.41 6.41 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.17 8.17 8.17 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.44 7.44 7.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.47 8.48 8.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database