CHEMBL1834247


SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](C)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O
InChIKey NTLGBVODVYUHJV-XGRCMKMKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 5
Rotatable bonds 8
Molecular weight (Da) 495.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 10.33 10.33 10.33 ChEMBL
δ OPRD Human Opioid A pKi 7.75 7.75 7.75 ChEMBL
μ OPRM Human Opioid A pKi 6.77 6.77 6.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pEC50 7.75 7.75 7.75 ChEMBL
δ OPRD Human Opioid A pEC50 9.77 9.77 9.77 ChEMBL
μ OPRM Human Opioid A pEC50 10.08 10.08 10.08 ChEMBL