CHEMBL1834409


SMILES CCC(C)(C)[C@](C)(O)[C@H]1C[C@@]23CC[C@]1(OC)[C@@H]1Oc4c(O)ccc5c4[C@@]12CCN(CC1CC1)[C@@H]3C5
InChIKey HBENZIXOGRCSQN-JLXZXSBASA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 481.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.07 8.07 8.07 ChEMBL
δ OPRD Human Opioid A pKi 8.8 8.8 8.8 ChEMBL
κ OPRK Human Opioid A pKi 8.25 8.25 8.25 ChEMBL
μ OPRM Human Opioid A pKi 8.67 8.67 8.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.11 7.11 7.11 ChEMBL
μ OPRM Human Opioid A pEC50 8.22 8.22 8.22 ChEMBL