CHEMBL186735


SMILES Cc1cc2c(CC(=O)O)cccc2n1C(=O)c1ccc(OCCOc2ccccc2)cc1
InChIKey BCXKWNRNWURDCY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 429.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pKi 8.0 8.0 8.0 ChEMBL
EP1 PE2R1 Mouse Prostanoid A pKi 5.25 5.25 5.25 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 6.27 6.27 6.27 ChEMBL
DP1 PD2R Human Prostanoid A pKi 6.54 6.54 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pIC50 7.3 7.3 7.3 ChEMBL
DP1 PD2R Human Prostanoid A pIC50 6.6 6.6 6.6 ChEMBL