CHEMBL191039


SMILES O=C(Nc1cc(-c2ccccc2)nn1-c1ccccc1)c1ccccc1
InChIKey AYVLYDAJDALPHK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 339.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.38 5.38 5.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 6.52 6.61 6.69 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 7.4 7.4 7.4 ChEMBL