BMS-986187


SMILES O=C1CC(C)(C)CC2=C1C(c1ccc(cc1)OCc1ccccc1C)C1=C(O2)CC(CC1=O)(C)C
InChIKey UEKIYVKPQNKSDI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.15 8.15 8.15 Guide to Pharmacology
μ OPRM Rat Opioid A pKi 7.2 7.2 7.2 Guide to Pharmacology
δ OPRD Human Opioid A pKi 8.15 8.32 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.52 7.52 7.52 ChEMBL
μ OPRM Human Opioid A pEC50 5.58 5.58 5.58 ChEMBL