CHEMBL1928133


SMILES CCOCCOc1ccn2ncc(C(=O)NCCCN3CCN(c4ccccc4OC)CC3)c2c1
InChIKey BEYYMPWIMDYWDO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 481.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A Q9TSW7 Pig Adrenoceptors A pKi 8.02 8.02 8.02 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.54 5.54 5.54 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.16 7.16 7.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.11 7.11 7.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.54 7.87 8.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database