BNTX


SMILES O=C1/C(=C\c2ccccc2)/C[C@@]2([C@@]34[C@H]1Oc1c4c(C[C@H]2N(CC3)CC2CC2)ccc1O)O
InChIKey WXOUFNFMPVMGFZ-XEGDMQTMSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 429.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.4 8.4 8.4 Guide to Pharmacology
κ OPRK Human Opioid A pKi 8.4 8.4 8.4 Guide to Pharmacology
μ OPRM Human Opioid A pKi 8.8 8.8 8.8 Guide to Pharmacology
δ OPRD Mouse Opioid A pKi 9.2 9.2 9.2 Guide to Pharmacology
δ OPRD Human Opioid A pKi 8.43 8.59 8.74 ChEMBL
μ OPRM Human Opioid A pKi 7.74 8.25 8.77 PDSP Ki database
δ OPRD Human Opioid A pKi 8.43 8.7 9.18 PDSP Ki database
κ OPRK Human Opioid A pKi 7.26 7.84 8.43 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 8.15 8.15 8.15 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 8.38 8.38 8.38 PDSP Ki database
μ OPRM Human Opioid A pKi 8.72 8.72 8.72 ChEMBL
δ OPRD Rat Opioid A pKi 8.7 8.7 8.7 Guide to Pharmacology
κ OPRK Guinea pig Opioid A pKi 7.18 7.32 7.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database