CHEMBL1956191


SMILES CC(Oc1ccccc1Cl)C1=NCCN1
InChIKey ARHDCTCZSSOSFG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 224.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.48 6.48 6.48 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.31 6.31 6.31 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.54 7.54 7.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.79 6.79 6.79 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 6.78 6.78 6.78 ChEMBL