CHEMBL1963026


SMILES O=S(=O)(c1cc(F)cc(F)c1)c1ccc2c(c1)O[C@H]1CNCC[C@@H]21
InChIKey FECXTVAJHWAPLK-RDJZCZTQSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 351.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Rat 5-Hydroxytryptamine A pKi 5.66 6.21 6.76 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.78 7.17 7.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 5.87 6.45 7.02 ChEMBL