CHEMBL2011441


SMILES COc1nc(Br)cnc1NS(=O)(=O)c1ccc(Cl)s1
InChIKey TZYSLHTWOJFPSJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 382.9

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR5 CCR5 Human Chemokine A pKd 4.54 4.6 4.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR4 CCR4 Mouse Chemokine A pIC50 8.3 8.3 8.3 ChEMBL
CCR4 CCR4 Human Chemokine A pIC50 6.7 6.95 7.2 ChEMBL