CHEMBL2037430


SMILES Clc1ccc(N2CCN(CCCc3nc4ccccc4s3)CC2)cc1
InChIKey KLXKCCCIYMYATJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 371.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.89 5.89 5.89 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.33 5.33 5.33 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.67 6.67 6.67 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.44 7.44 7.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.63 5.63 5.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database