CHEMBL2037519


SMILES O=C(CCCN1CCN(c2ncccn2)CC1)c1nc2ccccc2s1
InChIKey ITMQGDDPFZOVDW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 367.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.29 7.29 7.29 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.61 5.61 5.61 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.82 5.82 5.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database