CHEMBL207488


SMILES Fc1ccc(N2CCN(Cc3cn4nc(Cl)ccc4n3)CC2)cc1
InChIKey KLWCGZRXATXKMS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 345.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.16 5.16 5.16 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.4 8.4 8.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.25 5.25 5.25 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.92 4.96 5.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database