CHEMBL210005


SMILES C[C@H]1[C@H]2Cc3ccc(C(=O)NCCc4ccc(-c5ccccc5)cc4)cc3[C@]1(C)CCN2CC1CC1
InChIKey GZDNGLGWJBOMSN-XAEFOYQYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 478.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.62 9.62 9.62 ChEMBL
κ OPRK Human Opioid A pKi 9.46 9.46 9.46 ChEMBL
μ OPRM Human Opioid A pKi 9.6 9.6 9.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.16 8.16 8.16 ChEMBL
κ OPRK Human Opioid A pEC50 8.49 8.49 8.49 ChEMBL
μ OPRM Human Opioid A pEC50 8.52 8.52 8.52 ChEMBL