CHEMBL2111837


SMILES CN1c2ccc(Cl)cc2C(c2ccccc2)=NC[C@@H]1CCNC(=O)c1cccs1
InChIKey JEZGMXQLYTYHBX-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 423.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 8.35 8.35 8.35 ChEMBL
δ OPRD Human Opioid A pKi 6.35 6.35 6.35 ChEMBL
κ OPRK Human Opioid A pKi 9.16 9.16 9.16 ChEMBL
μ OPRM Human Opioid A pKi 7.56 7.56 7.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database