carfentanil


SMILES CCC(=O)N(C1(CCN(CC1)CCc1ccccc1)C(=O)OC)c1ccccc1
InChIKey YDSDEBIZUNNPOB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 394.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.37 7.37 7.37 Guide to Pharmacology
δ A0A286XTF2 Guinea pig Opioid A pKi 8.48 8.48 8.48 Guide to Pharmacology
δ OPRD Human Opioid A pKi 8.48 8.48 8.48 ChEMBL
κ OPRK Human Opioid A pKi 7.37 7.37 7.37 ChEMBL
μ OPRM Human Opioid A pKi 10.15 10.38 10.62 ChEMBL
μ OPRM Rat Opioid A pKi 10.05 10.34 10.62 ChEMBL
κ OPRK Guinea pig Opioid A pKi 7.04 7.21 7.37 ChEMBL
μ OPRM Mouse Opioid A pKi 10.62 10.62 10.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 7.77 7.77 7.77 ChEMBL