CHEMBL212575


SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(C2Cc3cccc4cccc2c34)CC1
InChIKey OGLIFFKVFKYPEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.0 8.0 8.0 ChEMBL
δ OPRD Human Opioid A pKi 5.56 5.56 5.56 ChEMBL
κ OPRK Human Opioid A pKi 6.17 6.17 6.17 ChEMBL
μ OPRM Human Opioid A pKi 6.58 6.58 6.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 4.26 4.26 4.26 ChEMBL