CHEMBL213834


SMILES CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3cccc4ccccc34)c3ccccc32)CC1
InChIKey VTTMDSGFQMHASZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 495.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.01 6.01 6.01 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.05 6.05 6.05 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.42 8.42 8.42 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.34 6.34 6.34 ChEMBL
D5 DRD5 Human Dopamine A pKi 6.98 6.98 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database