CHEMBL214312


SMILES c1nc([C@H]2C[C@@H]2CCNCC2CCCCC2)c[nH]1
InChIKey NESASFDNMLPZIR-KBPBESRZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 247.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.9 6.9 6.9 ChEMBL
H3 HRH3 Human Histamine A pKi 8.28 8.28 8.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 5.82 5.82 5.82 ChEMBL
H3 HRH3 Human Histamine A pIC50 7.43 7.43 7.43 ChEMBL