CHEMBL215895


SMILES CNC(=O)[C@H](Cc1ccc2ccccc2c1)N1CCN(C(=O)[C@@H](Cc2ccc(F)cc2)NC(=O)C2Cc3ccccc3CN2)[C@@H](CCCN=C(N)N)C1=O
InChIKey AIVKUJJDLDHLNN-HMVKWVIFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 5
Rotatable bonds 13
Molecular weight (Da) 734.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 6.5 6.5 6.5 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.45 6.45 6.45 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 6.98 6.98 6.98 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.79 6.79 6.79 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 8.8 8.8 8.8 ChEMBL