CHEMBL2159458


SMILES O=S(=O)(NCC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1ccc(F)cc1
InChIKey BQDBCWZXPYWQGM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 468.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.34 7.34 7.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database